VANCOMYCIN THERAPEUTIC & CRITICAL VALUES CHANGES

Thursday, September 24, 2009 at 10:39:43 AM

Effective immediately, the following changes will be adopted by the laboratory with regard to Vancomycin test reporting:

1.) Vancomycin Trough ranges, previously reported as 5-10 ug/mL, will now be reported as 10-20 ug/mL. Any value greater than 20 ug/mL will be considered a critical value and will be called by the laboratory.

2.) Vancomycin Peak ranges will continue to be reported as 30-40 ug/mL. Any value greater than 40 ug/mL will be considered a critical value and will be called by the laboratory.

3.) Random Vancomycin test results will continue to be reported without a range. Any value greater than 40 ug/mL will be considered a critical value and will be called by the laboratory.

In addition, the following guidelines have been suggested with regards to draw times for each of the Vancomycin tests offered by the laboratory:

1.) Vancomycin Trough levels should be drawn within an hour prior to the drug being administered to the patient.

2.) Vancomycin Peak levels should be drawn approximately one hour after completion of drug infusion.

3.) Vancomycin Random levels are not related to timing prior to or after drug administration, but the time of draw should be noted before submission to the laboratory.

These changes have been made in conjunction with the pharmacy department and reflect the current trends with regards to Vancomycin efficacy and toxicity. Any questions regarding laboratory values and/or reports should be directed to Angela K. Armato, MT, MBA, WMH Chemistry Supervisor 763-5780, or Rosemary Parkinson, MT, BGH Supervisor 763-2347.



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