TCELL NORMAL RANGE REVISIONS

Wednesday, July 27, 2011 at 1:19:44 PM

Effective immediately, the Flow Cytometry Department at UHS Wilson Laboratory will be revising the normal ranges for Tcell subsets for adults and children (0-1 and 1-5years old).

In some cases no adjustment in the ranges was necessary.

The old and new ranges are provided below:

%CD4(Helper T-cells)

Adult Old Range 29-61 New Range 34-56

Children (0-1yrs) Old Range 31-68 New Range 31-68

Children (1-5yrs) Old Range 31-54 New Range 31-54


Absolute CD4

Adult Old Range 430-1760 New Range 600-1600

Children (0-1yrs) Old Range 680-4855 New Range 680-4855

Children (1-5yrs) Old Range 570-2550 New Range 570-2550


%CD8(Suppressor T-cells)

Adult Old Range 11-38 New Range 11-38

Children (0-1yrs) Old Range 8-25 New Range 8-25

Children (1-5yrs) Old Range 13-33 New Range 13-33


Absolute CD8

Adult Old Range 170-1050 New Range 200-1000

Children (0-1yrs) Old Range 113-1775 New Range 113-1775

Children (1-5yrs) Old Range 365-1265 New Range 365-1265


CD3%(T-cells)

Adult Old Range 60-85 New Range 63-84

Children (0-1yrs) Old Range 48-86 New Range 48-86

Children (1-5yrs) Old Range 59-81 New Range 59-81


Absolute CD3

Adult Old Range 720-2330 New Range 1000-2300

Children (0-1yrs) Old Range 962-6480 New Range 962-6480

Children (1-5yrs) Old Range 1050-4185 New Range 1050-4185


%CD19(B-cells)

Adult Old Range 4-22 New Range 5-21

Children (0-1yrs) Old Range 10-39 New Range 10-39

Children (1-5yrs) Old Range 11-34 New Range 11-34


Absolute CD19

Adult Old Range 75-588 New Range 140-600

Children (0-1yrs) Old Range NA New Range 300-3000

Children (1-5yrs) Old Range NA New Range 390-1400


%CD16+56(NK cells)

Adult Old Range 6-31 New Range 4-21

Children (0-1yrs) Old Range 1-15 New Range 2-10

Children (1-5yrs) Old Range 2-10 New Range 2-10


Absolute CD16+56

Adult Old Range 100-430 New Range 100-430

Children (0-1yrs) Old Range NA New Range 160-1100

Children (1-5yrs) Old Range NA New Range 130-720


CD4/CD8 Ratio

Adult Old Range 0.9-3.6 New Range 1.00-4.00

Children (0-1yrs) Old Range 1.40-4.50 New Range 1.00-4.50

Children (1-5yrs) Old Range 0.8-2.80 New Range 1.00-4.00

These revisions are based on data obtained from the UHS patient population (including adult and pediatric patients) along with current published normal ranges for these analytes.

If there are any questions please contact Karen Stone, MT at 763-5509. Thank you.



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